Keeping you up to date with the happenings of the best Ob/Gyn residency program in the country!
Residency 2014-15
Sunday, August 8, 2010
Nice work Anna!
There is a great showing this weekend at the Infectious Diseases Society of OB/GYN. Our Program Director Jeff Peipert is joined by one of our fantastic attendings - Jenifer Allsworth. Also in the group is one of our interns, Anna Graseck. I'll let one of her co-residents have the blog...
"Wishing the best of luck to R1 Anna Graseck who is presenting at this weekend's 37th Annual Meeting for the Infectious Diseases Society of Obstetrics and Gynecology. Only a few months into intern year and already presenting at a conference- that's the WashU OBGYN way! Congrats Anna!" - R1 Natalia Grindler
Proposal Title: Comparison of an Observational Cohort Study and a Randomized Trial of Home versus Clinic-based Screening for Sexually Transmitted Infections in Long-Acting Reversible Contraceptive Users Anna S. Graseck, MD, Gina M. Secura, PhD, MPH, Jenifer E. Allsworth, PhD, Tessa Madden, MD, MPH, and Jeffrey F. Peipert, MD, PhD
Proposal Abstract:
Objective: To assess whether there are meaningful differences in the results of an observational cohort study (OBS) compared to a randomized clinical trial (RCT) of home versus clinic-based screening for sexually transmitted infections (STIs). Methods: We compared two studies (OBS and RCT) performed in women enrolled in the Contraceptive Choice Project. The OBS study consisted of the first 462 women enrolled. Participants were offered a choice of home versus clinic-based testing at the 12-month time point. All testing and treatment were free to participants and their partners. Subjects in the clinic group could screen at a local family planning clinic or their regular provider. The RCT randomized a distinct sample of 565 women using long-acting reversible contraception (LARC) to home versus clinic-based testing. We analyzed the rates of screening (test received) by group using Poisson regression with robust error variance, and compared the OBS and RCT studies. Results: In the OBS study, women were more likely to choose to screen for STIs at home (76%) than at a clinic (16%) or with their own medical provider (8%, P<.001). Slightly more than half of the participants (57%) completed screening. Participants in the OBS study who chose home-based testing were more likely to complete a test compared with clinic-based testing (65% v. 23%, RR 2.8, 95% CI 1.9–4.0). In the RCT, the subjects in the home group were more likely submit a test than the clinic group, and the effect estimate was very similar (56% v. 22%, RR 2.5, 95% CI 2.0-3.2). Conclusion: In both the OBS and RCT, subjects were more likely to be tested for STIs with home-based, self-collected testing. This analysis demonstrates that the internal validity of an observational study can be quite high, even when compared to the gold-standard RCT. Mechanisms to facilitate home-based testing should be further explored.
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